What the loading envelope is
Every formula has a finite loading capacity. The envelope is where it ends.
NanoBase™ is a cosmetic raw material: the Architecture your finished formula is built on, used as one line item at its use level. It is a tri-domain nano-colloidal Architecture with nanocolloidal, nanoliposomal and nanomicellar domains, designed to an electrostatic (DLVO) stabilisation specification, engineered to a ~185 nm design target and DLS-characterised every batch. Every oil, peptide, gum and salt you add on top draws on a fixed amount of interfacial area and a fixed electrostatic charge budget. The loading envelope is the set of category limits inside which the Architecture stays intact: sub-micron, tri-domain and electrostatically stabilised.
Inside the envelope, added ingredients are designed to partition into the three domains. Outside it, the failure is structural: coverage falls below the threshold that keeps droplets apart, the surface charge reserve is spent, or free polymer above its overlap concentration drives depletion flocculation. Downstream processing is cold by design, so none of that can be repaired after the fact. Staying inside the envelope is how a build comes out right the first time.
Oils & lipidsSurface, not solubility
Added oil grows the droplet and spreads the same stabiliser over more surface. Past a point, coverage drops below the level that keeps droplets from coalescing. Heavier, non-volatile oils buy more room than light volatile ones.
Water-soluble activesUsually the roomiest category
Small molecules and water-soluble peptides have ample headroom, but they draw interfacial coverage down slightly, so they trade against your oil load rather than being independent of it.
Anchoring peptidesA fixed number of seats
Lipidated (palmitoyl / myristoyl) peptides insert into the bilayer leaflet, which has a finite number of insertion sites. Two anchoring peptides compete for the same space: one well-placed peptide beats two that fight over it.
Charge & saltThe charge has a budget
Cationic actives and salt-form polymers draw down the surface charge reserve. Spend it and the stabilising charge drifts toward the flocculation threshold, which is why added electrolyte is a quiet way to break an otherwise good formula.
Gums & polymersDepletion, not incompatibility
Free non-adsorbing polymer above its overlap concentration c* flocculates the formula however strong the surface charge is. An adsorbing / associative thickener, or a lower-molecular-weight grade, keeps your texture without the penalty.
What NanoBase™ ships withPreserved raw material, not a moisturizer
NanoBase™ ships fully preserved. Additional preservative in your finished formula may or may not be needed depending on what you add, and Preservative Efficacy Testing (PET, ISO 11930 / USP <51>) is always recommended. It does not contain humectants or emollients; those are yours to formulate on top.
